Do not use linezolid if you have used an MAO inhibitor in the past 14 days. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. Probiotics can also help restore the gut bacteria after antibiotics. Dosage Considerations - Should be Given as Follows: Genitourinary Tract Infections Adult: 250 mg orally every 6 hours; dosage range, 1-4 g/day in divided doses Pediatric: 25-50 mg/kg/day orally divided every 6-8 hours for 10 days; not to exceed 4 g/day Bone Infections Adult: 250 mg orally every 6 hours; dosage range, 1-4 g/day in divided doses However, they can sometimes cause side effects, such as diarrhea and liver damage. Inhibition of MAO can result in high levels of tyramine, potentially causing a hypertensive crisis (i.e dangerously high blood pressure). Thank. One study found that consuming red wine polyphenol extracts for four weeks could significantly increase the amount of healthy Bifidobacteria in the intestines and reduce blood pressure and blood cholesterol (31). Also, do not use this medicine if you or your child are also using the following medicines: buspirone (Buspar), dobutamine (Dobutrex), dopamine (Intropin), epinephrine (Adrenalin), norepinephrine (Levophed), cold medicines or decongestants (eg, phenylpropanolamine, pseudoephedrine, or Sudafed), medicine to treat depression (eg, amitriptyline, bupropion, doxepin, fluoxetine, nortriptyline, paroxetine, Celexa, Effexor, Elavil, Lexapro, Paxil, or Zoloft), medicine to treat migraine headaches (eg, sumatriptan, zolmitriptan, Axert, Imitrex, or Zomig), or narcotic pain medicines (eg, meperidine, Demerol). Your doctor may decide not to treat you with this medication or change some of the other medicines you take. When protein begins to break down, tyramine is formed, according to the Micromedex database. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Some foods can reduce these side effects, while others may make them worse. If a list of these foods and beverages is not given to you, ask your doctor to provide one. You can take it before, with or after food. But when you're already feeling unwell and having to manage an infection, suddenly changing your entire routine can be hard. Infection at the catheter siteShould not be used in patients with this condition. Copyright 2023 Leaf Group Ltd., all rights reserved. However, if overused, they can cause long-term changes to healthy gut bacteria and contribute to liver damage. With the exception of yogurt, avoid dairy, said Kohlstadt. MAO is a complex enzyme system in the body and inhibition of MAO can result in an increased concentration of neurotransmitters (e.g. Thus, eating prebiotic foods after antibiotics may help the growth of beneficial gut bacteria that have been damaged by antibiotics. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. You should not use this medicine at is resistant to medication if you have untreated or uncontrolled high blood pressure, a carcinoid tumor, adrenal gland tumor, or a severely overactive thyroid. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Some medicines can interact with linezolid and cause a serious condition called serotonin syndrome. Foods and beverages that have been pickled, smoked, or fermented usually contain tyramine. If you notice any other effects, check with your healthcare professional. Other studies have also found that fermented foods may be beneficial during antibiotic treatment. What special precautions should I follow? Usually avoid combinations; use it only under special circumstances. Keep using this medicine for the full time of treatment, even if you or your child begin to feel better after a few days. This often takes a lot of the good bacteria with it. Thus, it is important to take antibiotics and probiotics a few hours apart. Cheese and meat: antibiotics. Zyvox (linezolid) is not a commonly used antibiotic, but not necessarily because the drug is unsafe. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Call your doctor for medical advice about side effects. Call your doctor right away if you or your child feel very tired, weak, or nauseated, if you vomit or have trouble breathing, or if you feel lightheaded or fainting. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Linezolid will not treat a viral infection such as the flu or a common cold. Take linezolid until you finish the prescription, even if you feel better. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you are taking fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), or have stopped taking it within the past 5 weeks. Zyvox, while easily dosed, does have restrictions when it comes to food intake. You should avoid caffeinated beverages like coffee, tea, soft drinks and energy drinks when taking ciprofloxacin. Common foods high in tyramine include: Be sure to follow a strict diet of low tyramine foods while taking Zyvox to prevent any sort of reaction. You should take it regularly as per the schedule prescribed by your doctor. On the flip side, you also need to be careful taking certain vitamins and probiotics with cephalexin, which can block the absorption of the antibiotic. Whats more, eating high-fiber foods, fermented foods and prebiotic foods after taking antibiotics may also help reestablish a healthy gut microbiota. Do not use if the medicine has particles in it. All rights reserved. According to doctors at the Mayo Clinic, dangerous interactions arise between antibiotics and grapefruit because chemicals in the fruit interfere with the way enzymes metabolize the medication. Tyramine is present in certain foods. Version: 11.02. Your prescription is probably not refillable. Minimally clinically significant. It is very important that your doctor check your or your child's progress while you are taking this medicine, to see if the medicine is working properly. The following information includes only the average doses of this medicine. low blood cell counts - fever, chills, tiredness, weakness, confusion, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. I have bad allergies! For example, studies have shown that it can be harmful to consume grapefruit and grapefruit juice while taking certain medications, including antibiotics (34, 35). If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. If you regularly consume dietary supplements, play it safe by avoiding danshen, licorice, St. John's wort, coenzyme Q-10, evening primrose, garlic, ginseng, saw palmetto, hawthorn and ginkgo biloba, as all of these impact the effectiveness of antibiotics, and can lead to an increased risk of bleeding, low blood pressure, irregular heartbeat, and more. This medicine may cause diarrhea, and in some cases it can be severe. If you can, avoid people with infections. When taken with certain foods or drinks, linezolid can cause an increase in blood pressure. Contact your doctor if you have questions about any foods. Avoid foods made with beer and wine including beer battered fish, bread made with beer and fondue. Highly clinically significant. Studies have shown that foods supplemented with calcium can reduce the absorption of various antibiotics, including ciprofloxacin (Cipro) and gatifloxacin (37, 38). Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during treatment with this medicine. Also tell your doctor if you are taking the following medications or have stopped taking them within the past two weeks: bupropion (Aplenzin, Wellbutrin, Zyban, others); buspirone; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), sertraline (Zoloft), and vilazodone (Vilbyrd); serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), and venlafaxine (Effexor); and tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin. Single courses of the antibiotic can cost thousands of dollars and insurance companies typically require patients to try alternative therapies first. Avoid prepared foods which contain yeast or yeast extracts including canned and frozen foods; read product labels carefully. Keflex Panixine DisperDose Canadian Brand Name Novo-Lexin Descriptions Cephalexin is used to treat bacterial infections in many different parts of the body. Read More: Allergic Rash From Antibiotics. This is due to the way antibiotics disrupt the balance of bacteria in your intestines. To help keep the amount constant, linezolid must be given on a regular schedule. If you have any questions about this, check with your pharmacist. Can I Take Vitamins If I Am Taking Antibiotics? It is usually taken with or without food twice a day (every 12 hours) for 10 to 28 days. Vancomycin-resistant enterococcal (VRE) infections, MRSE (Methicillin-resistant Staphylococcus aureus). Find them in kefir, yogurt, and even fortified cereals. What should I know regarding pregnancy, nursing and administering Linezolid to children or the elderly? Inappropriate and overuse of the drug has led to an increase in resistant organisms and generally, alternative treatments are to be considered prior to using Zyvox, especially in an outpatient setting. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. If you have any questions about this, check with your pharmacist. Zyvox may also be used for purposes not listed in this medication guide. 3 Commonly prescribed calcium channel blockers include Cardene (nicardipine), Cardizem (diltiazem), Norvasc (amlodipine), Procardia (nifedipine), and Verelan (verapamil . Our website services, content, and products are for informational purposes only. Unlike probiotics, which are live microbes, prebiotics are foods that feed the good bacteria in your gut. infection due to vancomycin-resistant Enterococcus faecium, bacterial pneumonia caused by Streptococcus, bacterial pneumonia caused by Staphylococcus, skin infection due to Staphylococcus aureus bacteria, skin infection due to Streptococcus pyogenes bacteria, complicated skin infection due to Staphylococcus aureus bacteria, complicated skin infection by Streptococcus agalactiae, Complicated skin infection due to Strep. Things to remember when you fill your prescription. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Mayo Clinic: "I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Talk to your doctor or pharmacist if you have any questions or concerns. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor. It works by killing bacteria or preventing their growth. Be sure to mention any of the following: epinephrine (EpiPen); meperidine (Demerol); medications for migraine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); phenylpropanolamine (no longer available in the US); and pseudoephedrine (Sudafed; in many cold or decongestant medications). Linezolid is used to treat certain bacterial infections in many different parts of the body, including certain types of skin infections or pneumonia. If you want to check that your medicines are safe to take with your antibiotics, ask your GP or local pharmacist. These foods and beverages include alcoholic beverages, especially beer, Chianti, and other red wines; alcohol-free beer; cheeses (especially strong, aged, or processed varieties); sauerkraut; yogurt; raisins; bananas; sour cream; pickled herring; liver (especially chicken liver); dried meats and sausage (including hard salami and pepperoni); canned figs; avocados; soy sauce; turkey; yeast extracts; papaya products (including certain meat tenderizers); fava beans; and broad bean pods. These include: Aged cheeses Aged, smoked, pickled, or processed meats and fish Alcohol (beer, wine, liqueur) Fruits, including avocados, bananas, figs, raisins Soy sauce Miso soup Yeast/protein extracts Bean curd Also, do not use this medicine if you or your child are also using the following medicines: buspirone (Buspar), dobutamine (Dobutrex), dopamine (Intropin), epinephrine (Adrenalin), norepinephrine (Levophed), cold medicines or decongestants (eg, phenylpropanolamine, pseudoephedrine, or Sudafed), medicine to treat depression (eg, amitriptyline, bupropion, doxepin, fluoxetine, nortriptyline, paroxetine, Celexa, Effexor, Elavil, Lexapro, Paxil, or Zoloft), medicine to treat migraine headaches (eg, sumatriptan, zolmitriptan, Axert, Imitrex, or Zomig), or narcotic pain medicines (eg, meperidine, Demerol). Prepare your injection only when you are ready to give it. 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