Coadministration may result in a significant decrease in renal function. Minor/Significance Unknown. Either increases toxicity of the other by pharmacodynamic synergism. This website also contains material copyrighted by 3rd parties. Minor/Significance Unknown. Use Caution/Monitor. Long term (>1 wk) NSAID use. Monitor Closely (2)oxaprozin decreases effects of betaxolol by pharmacodynamic antagonism. Increased risk of GI ulceration. metoprolol and oxaprozin both increase serum potassium. Avoid or Use Alternate Drug. NSAIDs decrease prostaglandin synthesis. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. Use Caution/Monitor. Effect of interaction is not clear, use caution. The SNRI duloxetine resulted in moderate improvements in short-term pain and small improvements in short-term function and quality of life compared with placebo for people with diabetic peripheral neuropathy. celiprolol and oxaprozin both increase serum potassium. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Coadministration of baricitinib with strong organic anion transporter 3 (OAT3) inhibitors is not recommended. propionic acids (naproxen and ibuprofen) enolic acids (meloxicam and piroxicam) acetic acids (diclofenac and indomethacin) naphthylalanine (nabumetone) selective COX-2 inhibitors (celecoxib . Monitor Closely (2)oxaprozin decreases effects of esmolol by pharmacodynamic antagonism. Dr. Tracy Lovell answered. Comment: Combination may increase GI bleeding, ulceration and irritation. Use Caution/Monitor. Use Caution/Monitor. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Use Caution/Monitor. Use Caution/Monitor. oxaprozin, betrixaban. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor Closely (1)mesalamine, oxaprozin. Increased risk of GI ulceration. Use Caution/Monitor.oxaprozin decreases effects of nebivolol by pharmacodynamic antagonism. Monitor Closely (1)oxaprozin decreases effects of phenoxybenzamine by pharmacodynamic antagonism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. See below: You cannot take both as they are in the same class of medications and both together could put you at risk for a GI bleed or kidney damage. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Minor/Significance Unknown. Otherwise, call a poison control center right away. Use Caution/Monitor. There are conflicting reports from studies of either increased or decreased IOP when ophthalmic prostaglandins are coadministered with NSAIDs (either systemic or ophthalmic). Zanubrutinib-induced cytopenias increases risk of hemorrhage. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (2)mefenamic acid and oxaprozin both increase anticoagulation. You should not use this medication after 30 weeks of pregnancy.It is unknown if this drug passes into breast milk. oxaprozin and tolfenamic acid both increase anticoagulation. Long term (>1 wk) NSAID use. Use Caution/Monitor.Serious - Use Alternative (1)oxaprozin, ketorolac intranasal. Use Caution/Monitor. rose hips will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Amoxicillin is used to treat a wide variety of bacterial infections. Modify Therapy/Monitor Closely. Either increases levels of the other by decreasing renal clearance. NSAIDs decrease prostaglandin synthesis. Modify Therapy/Monitor Closely. Monitor Closely (2)flurbiprofen and oxaprozin both increase anticoagulation. Use Caution/Monitor.pivmecillinam, oxaprozin. Talk to your doctor if you are using marijuana (cannabis).This medicine may cause stomach bleeding. Take your next dose at the regular time. oxaprozin will increase the level or effect of willow bark by acidic (anionic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or. Use Caution/Monitor. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Oxaprozin is known as a nonsteroidal anti-inflammatory drug (NSAID).If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. Effect of interaction is not clear, use caution. oxaprozin, benazepril. Monitor Closely (1)ibrutinib will increase the level or effect of oxaprozin by anticoagulation. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. (Theoretical interaction) Combination may have additive nephrotoxic effects. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (2)oxaprozin and salicylates (non-asa) both increase anticoagulation. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. Defibrotide may enhance effects of platelet inhibitors. SSRIs inhib. Minor/Significance Unknown. Comment: Risk of CNS stimulation/seizure. Monitor Closely (1)oxaprozin and phytoestrogens both increase anticoagulation. Monitor Closely (1)oxaprozin increases and levalbuterol decreases serum potassium. You can use the study as a second opinion to make health care decisions. It is not recommended for use in pregnancy from 20 weeks until delivery. Minor/Significance Unknown. Monitor Closely (1)oxaprozin increases and norepinephrine decreases serum potassium. When using Mobic 7.5 mg or any other dose, the medication usually acts within 1 hour and should be taken only once a day. Use Caution/Monitor. Avoid or Use Alternate Drug. diclofenac and oxaprozin both increase anticoagulation. oxaprozin will increase the level or effect of salsalate by acidic (anionic) drug competition for renal tubular clearance. Serious - Use Alternative (1)oxaprozin increases levels of pemetrexed by unspecified interaction mechanism. Either increases toxicity of the other by Other (see comment). oxaprozin decreases effects of irbesartan by pharmacodynamic antagonism. Monitor Closely (2)naproxen and oxaprozin both increase anticoagulation. Interaction mainly occurs in preterm infants. NSAIDs decrease prostaglandin synthesis. Modify Therapy/Monitor Closely. Monitor Closely (1)oxaprozin and reteplase both increase anticoagulation. oxaprozin, hydrocortisone. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and epinephrine decreases serum potassium. Use Caution/Monitor. dabigatran and oxaprozin both increase anticoagulation. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Increased risk of GI ulceration. Use Caution/Monitor. Monitor Closely (3)sacubitril/valsartan, oxaprozin. Effect of interaction is not clear, use caution. penbutolol and oxaprozin both increase serum potassium. carvedilol and oxaprozin both increase serum potassium. Minor/Significance Unknown. oxaprozin increases levels of methotrexate by decreasing renal clearance. commonly, these are "preferred" (on formulary) brand drugs. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Use Caution/Monitor. prescription products. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. encoded search term (oxaprozin (Daypro)) and oxaprozin (Daypro), Medscape Rheumatologist Compensation Report 2018, Physical Medicine and Rehabilitation for Thoracic Outlet Syndrome. Use Caution/Monitor. oxaprozin and salsalate both increase serum potassium. oxaprozin and piroxicam both increase anticoagulation. NSAIDs decrease prostaglandin synthesis. Monitor Closely (1)oxaprozin decreases effects of terazosin by pharmacodynamic antagonism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. oxaprozin increases levels of vancomycin by decreasing renal clearance. Use Caution/Monitor. Use Caution/Monitor. oxaprozin increases and salmeterol decreases serum potassium. Common side effects of Daypro include rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation, heartburn, fluid retention, and shortness of breath. Use Caution/Monitor. Aqueous humor bioavailablity of oxaprozin is significantly increased, with a 4-fold greater area under the curve in the inflamed eye vs. the control Bucolo and Maltese (2002). Long term (>1 wk) NSAID use. There are conflicting reports from studies of either increased or decreased IOP when ophthalmic prostaglandins are coadministered with NSAIDs (either systemic or ophthalmic). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor.mefenamic acid and oxaprozin both increase serum potassium. Monitor Closely (1)oxaprozin decreases effects of zotepine by pharmacodynamic antagonism. ofloxacin, oxaprozin. Avoid administering other phototoxic drugs with aminolevulinic acid oral for 24 hr during perioperative period. Monitor Closely (2)nabumetone and oxaprozin both increase anticoagulation. Both drugs have the potential to cause bleeding, monitor closely. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. pharmacodynamic antagonism. Use Caution/Monitor.oxaprozin decreases effects of olmesartan by pharmacodynamic antagonism. Other (see comment). Use Caution/Monitor. SSRIs inhib. Use Caution/Monitor.indomethacin and oxaprozin both increase serum potassium. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, trandolapril. nebivolol and oxaprozin both increase serum potassium. oxaprozin increases levels of gentamicin by decreasing renal clearance. Effect of interaction is not clear, use caution. Adjust the pralatrexate dose as needed. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Either increases toxicity of the other by Other (see comment). Interaction mainly occurs in preterm infants. oxaprozin decreases effects of eplerenone by pharmacodynamic antagonism. Minor (1)cefpirome will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Daypro is a trading name for the parent Medicine Oxaprozin or Oxaprozinum. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Compare formulary status to other drugs in the same class. Minor/Significance Unknown. Monitor Closely (1)oxaprozin increases and gentamicin decreases serum potassium. Use Caution/Monitor.etodolac and oxaprozin both increase serum potassium. Modify Therapy/Monitor Closely. NSAIDs decrease prostaglandin synthesis. Monitor Closely (1)phenindione and oxaprozin both increase anticoagulation. Effect of interaction is not clear, use caution. Piroxicam has an estimated t1/2 of 50 hours. Avoid or Use Alternate Drug. mefenamic acid and oxaprozin both increase anticoagulation. Monitor Closely (2)celecoxib and oxaprozin both increase anticoagulation. drospirenone and oxaprozin both increase serum potassium. Contraindicated.Minor (1)ketorolac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. UGT inhibition; significance of interaction unclear. Use Caution/Monitor.meloxicam and oxaprozin both increase serum potassium. NSAIDs decrease prostaglandin synthesis. Minor/Significance Unknown. A key clinical question based on the AHRQ Effective Health Care Program systematic review of the literature is presented, followed by an evidence-based answer based on the review. meloxicam show some selectivity towards the COX-2 enzyme.41 Due to the variability in NSAID half-life . Either increases toxicity of the other by pharmacodynamic synergism. Minor (1)cephalexin will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. labetalol and oxaprozin both increase serum potassium. La principale motivation des uniparents qui se lancent dans la colocation est d'ordre financier. oxaprozin increases and vitamin K1 (phytonadione) decreases anticoagulation. diclofenac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and ethacrynic acid decreases serum potassium. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor Closely (2)ketorolac and oxaprozin both increase anticoagulation. Monitor Closely (1)oxaprozin and dong quai both increase anticoagulation. Caution is advised, both drugs have the potential to cause bleeding. serotonin uptake by platelets. Use Caution/Monitor. oxaprozin increases and metolazone decreases serum potassium. serotonin uptake by platelets. Use Caution/Monitor. Long term (>1 wk) NSAID use. oxaprozin, zanubrutinib. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, moexipril. pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. enalapril, oxaprozin. Avoid or Use Alternate Drug. Use Caution/Monitor. Oxaprozin (Daypro) 600 mg three times daily: $26 ($225) Piroxicam (Feldene) 20 mg daily: $15 ($133) Salsalate: 750 mg twice daily: $14 (NA) Sulindac (Clinoril) 150 mg twice daily: $19 (NA) 200 mg . Monitor Closely (1)oxaprozin increases effects of glimepiride by unknown mechanism. Use Caution/Monitor. Effect of interaction is not clear, use caution. Monitor Closely (1)oxaprozin increases and terbutaline decreases serum potassium. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. oxaprozin increases effects of tolbutamide by unknown mechanism. Use Caution/Monitor.Minor (1)oxaprozin decreases effects of furosemide by pharmacodynamic antagonism. The AHRQ review found that treatment with memantine resulted in moderate intermediate-term improvements in pain, function, and quality of life for fibromyalgia. Use Caution/Monitor. Minor (1)oxaprozin decreases effects of imidapril by pharmacodynamic antagonism. metolazone will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.Minor (1)chlorothiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Effect of interaction is not clear, use caution. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. pharmacodynamic antagonism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, ramipril. Use Caution/Monitor. Minor/Significance Unknown. Effect of interaction is not clear, use caution. celecoxib will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Avoid concurrent or sequential use to decrease risk for ototoxicity. Minor (1)oxaprozin will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Increased risk of upper GI bleeding. Other (see comment). Use Caution/Monitor. oxaprozin, tacrolimus. Monitor Closely (2)acemetacin and oxaprozin both increase anticoagulation. Chronic use of NSAIDs with prasugrel may increase bleeding risk. Increased risk of bleeding events. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Ibuprofen in its usual form needs to . Comment: Mechanism unknown. oxaprozin and forskolin both increase anticoagulation. 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